Can Manipulating Macros Help Metabolism While Dieting? | Biolayne
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Can Manipulating Macros Help Metabolism While Dieting?


The effects of dietary macronutrient composition on resting energy expenditure following active weight loss: A systematic review and meta-analysis.
Ho et al. (2024)
Can Manipulating Macros Help Metabolism While Dieting?

Overview

What did they find? This study evaluated how the percentage of low (≤20%), moderate (21-30%) or high (>30%) carbohydrate, fat, and protein intake changes REE after minimal (≤5%) or moderate to high (>5%) weight loss.

What did they test? In those who experienced moderate to high weight loss, a 1% increase in carbohydrate intake was associated with a reduction of 2.30 kcal/day in REE, a 1% increase in protein and fat intake was correlated with an increase in REE by 3.00 and 0.50 kcal/day, respectively.
What does it mean for you? While there may be a beneficial effect of substituting fats for carbohydrates in reducing the diet-induced decline in REE in individuals experiencing moderate to high weight loss (>5%), the magnitude of the benefit is questionable, and is unlikely to impact fat loss. Also, this meta-analysis has limitations which means the results should be interpreted with caution.


What’s the problem?

Purpose

There are several types of diets people use to lose weight. Previous meta-analyses suggest that as long as a diet is adhered to, most are effective in causing weight loss, irrespective of dietary macronutrient compositions 1 2. A closer examination of these meta-analyses reveals that lower carbohydrate (low-CHO) diets might have a small advantage over others. For example, low-CHO caused slightly more weight loss than low-fat diets over six months in a recent network meta-analysis (-4.63 v -4.37 kg) 1.

Type of DietPopular Diets*Carbohydrates, % kcalProtein, % kcalFat, % kcal
Low carbohydratesAtkins, South Beach, Zone≤ 40Approximately 3030-55
Moderate macronutrientsBiggest Loser, DASH, Jenny Craig, Mediterranean, Portfolio, Slimming World, Volumetrics, Weight WatchersApproximately 55-60Approximately 1521-≤30
Low fatOrnish, Rosemary ConleyApproximately 60Approximately 10-15≤20

After a diet, resting energy expenditure (REE) is decreased due to a reduction in body weight. Some research has shown that a low-CHO diet may prevent these declines 4. Specifically, one study found REE decreased less with a low-CHO diet compared with a low-fat diet 4. Others have found no differences on REE changes in high vs low carbohydrate diets 3. Since REE contributes to two-thirds of total energy daily expenditure (TDEE), its preservation following weight loss could help people maintain their weight loss after a diet 5. Therefore, the purpose of the current review and meta-analysis was to determine the level of evidence on macronutrient dietary patterns on weight management, with a focus on changes in the REE following weight loss.

Hypothesis

The authors did not state a specific hypothesis; rather, they used a meta-analysis to evaluate the overall impact of different dietary macronutrient compositions on REE following weight loss.


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About the author

About Brandon Roberts
Brandon Roberts

Brandon Roberts serves as the Chief Science Officer at Tailored Coaching Method. He has a PhD in Muscle Biology, an MS in Human Performance, and a BS in Molecular Biology, along with over a decade of experience as a strength coach. He completed a prestigious NIH postdoctoral fellowship in Exercise Medicine and Nutrition at the...[Continue]

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